finngen_R13_I9_VTE-PRISM_deCODE

PRISM, deCODE (SomaScan) × FinnGen R13. Each point is one protein: its PRISM model (cis and trans pQTL loci, pleiotropic hotspot loci excluded) tested against this phenotype's GWAS summary statistics. A positive effect means a higher genetically predicted protein level goes with a higher trait value or risk.

1,926 proteins tested (model R² ≥ 0.01 and more than 10 SNPs); 38 set aside by the FinnGen calibration check. 39 significant at a Benjamini–Hochberg FDR of 5%, computed over all traits of this panel × cohort scan (p ≤ 8.18e-05; dashed line). Methods and bulk downloads.